Jesse Menachem Ehrenfeld (born 1978) is an American physician. Ehrenfeld is Chair of the American Medical Association Board of Trustees and the Joseph A. Johnson Jr., Distinguished Leadership Professor of Anesthesiology, Surgery, Biomedical Informatics & Health Policy at Vanderbilt University School of Medicine. He is also a former Speaker of the Massachusetts Medical Society, where he was the youngest officer in the 228-year history of the organization. He is also a former Vice-President of the Massachusetts Society of Anesthesiologists. The inaugural recipient on the NIH Sexual and Gender Minority Research Award from the NIH Director, Ehrenfeld has been recognized for his contributions to advancing health equity. A 2008 recipient of the AMA Foundation Leadership Award, Ehrenfeld is a researcher in the field of biomedical informatics. Ehrenfeld's research interests include bioinformatics and the application of information technology to increase quality, reliability and patient safety. Ehrenfeld's work has led to the presentation of over 200 abstracts at national/international meetings and the publication of over 175 manuscripts in peer-reviewed journals. He serves as Editor-in-Chief of the Journal of Medical Systems, and is a fellow of the American Medical Informatics Association and the American Society of Anesthesiologists.