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Malcolm A. S. Moore, D.Phil. (born January 18, 1944) is the Enid A. Haupt Chair of Cell Biology at the Memorial Sloan-Kettering Cancer Center. Dr. Moore is a noted oncologist and hematologist primarily known for being the Principal Investigator in the development of filgrastim, marketed by Amgen under the brand name of Neupogen and Neulasta. Over 3 million patients world-wide, mostly with cancer, have been treated with Neupogen. G-CSF mobilizes stem cells from the bone marrow into the circulation and subsequent peripheral blood leukapheresis produces sufficient stem cells for both autologous or allogeneic transplantation, reducing the need to obtain large volumes of bone marrow. Such stem cell transplants give a faster recovery of white blood cells, platelets and red cells than seen with conventional bone marrow transplantation. G-CSF stem cell transplants are used in treatment of leukemia, lymphoma and multiple myeloma resulting in prolonged remission and, in some cases, cure. He is a member of various national and international societies and is on the editorial boards of a number of Journals. He has served or chaired committees of governmental and professional organizations.
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