Yves A. Lussier, M.D., Professional Engineer, is a physician-scientist conducting research in translational Bioinformatics. He pioneered the commercial use of controlled medical vocabulary organized as directed semantic networks in electronic medical records, as well as Pen computing for clinicians. Associate Professor of Medicine at The University of Chicago, he currently directs of Center for Biomedical Informatics (CBI), is Associate Director for Informatics of the Cancer Center, and joint Director for Informatics of the Institute for Translational Medicine (CTSA). He is a fellow of the Institute for Genomics and Systems Biology and of the Computation Institute. From 2001-6, he served as Dir. of Technology transfer and Assist Prof. at Columbia University Depts. of Medicine and of Biomedical Informatics, Center for Computational Biolology and Bioinformatics (C2B2) and Columbia Joint Center for Systems Biology. Dr. Lussier works in both clinical medicine and engineering practice. He was appointed as the General Chair of the 2009 American Medical Informatics Association (AMIA) Summit on Translational Bioinformatics and has made significant contribution to the emerging field of translational bioinformatics and personalized medicine. He serves on the editorial board of the Journal of Biomedical Informatics, Journal of the American Medical Informatics Association, and on the Journal of Personalized Medicine. Dr. Lussier is an elected Fellow of American College of Medical Informatics. He published many research papers in journals such as PLoS Computational Biology, BMC Genomics, BMC Bioinformatics, Bioinformatics (Oxford University Press) in medical informatics and personalized medicine.